英文医学论文摘要翻译练习

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摘要翻译练习

1. 中药灯盏细辛注射液治疗急性缺血性脑卒中：随机对照试验的系统评价和荟萃分析

Chinese herbal medicine Dengzhan Xixin injection for acute ischemic stroke: A systematic review and meta-analysis of randomised controlled trials

目的 评价中药灯盏细辛注射液治疗急性缺血性脑卒中的有效性和安全性。

方法 在6个电子数据库中，使用计算机检索有关灯盏细辛注射用于急性缺血性脑卒中的随机对照试验，使用Cochrane偏倚风险工具评估随机对照试验的方法学质量。使用RevMan 5.3进行数据合成，并给出平均差异或相对风险及其95％置信区间。使用GRADEpro（版本3.6）生成研究发现结果的总结表。

结果 共纳入25项随机对照临床试验，含有2498名参与者，所有试验均采用在双臂的常规治疗。大多数研究具有较高的偏倚风险。 在治疗期间（14-35天），常规治疗合并灯盏细辛注射液没有明显改善死亡率（RR : 0.27，95％CI: 0.05至1.63），但是可以提高Barthel指数评分（MD: 10.20, 95％CI: 8.16至12.25），降低神经功能缺损评分（（MD: -3.99，95％CI：-5.68 至-2.30），根据NFDS方法; （MD: -1.67，95％CI：-2.59至-0.76），根据NIHSS方法），治疗失败率较低（RR: 0.40, 95％CI: 0.31至0.52）。13项试验（52％）报告了不良事件的结果，但未报告严重不良事件。

结论 低质量证据表明灯盏细辛注射夜似乎可改善急性缺血性卒中患者的神经功能。 但是，需要大规模和严格的临床试验来进一步研究这种可能的益处。

Objective To evaluate the effectiveness and safety of Chinese herbal medicine Dengzhan Xixin (Erigeron breviscapus) injection for acute ischemic stroke.

Methods Six electronic databases were searched for randomised controlled trials (RCTs) of Dengzhan Xixin (DZXX) injection for acute ischemic stroke. The methodological quality of RCTs was assessed by the Cochrane risk of bias tool.

Data synthesis was performed using RevMan 5.3 and was presented with mean difference (MD) or relative risk (RR) and their 95% confidence interval (CI). A summary of finding table was generated by GRADEpro (version 3.6).

Results Twenty-five RCTs with 2498 participants were included and all trials adopted conventional therapy (CT) in both arms. Most of the studies had high risk of bias.

The addition of DZXX to CT showed no significant benefit on death (RR 0.27, 95% CI 0.05–1.63) within the treatment period (14–35 d), but showed higher Barthel index score (MD 10.20, 95% CI 8.16–12.25), lower neurological function deficit score (MD −3.99, 95% CI −5.68 to −2.30, by NFDS; MD −1.67, 95% CI −2.59 to −0.76, by NIHSS), and lower treatment failure (RR 0.40, 95% CI 0.31–0.52). Thirteen trials (52%) reported the outcome of adverse events, but no serious adverse events were reported.

Conclusion Low quality evidence implied that DZXX injection appeared to improve neurological function in patients with acute ischemic stroke. However, this potential benefit should be further studied in large, rigorous trials.

2. 目的 运用Meta分析法评价中医药降低早期糖尿病肾病患者尿蛋白水平的疗效。 方法 计算机检索Medline、PubMed、Cochrane图书馆、中国生物医学文献数据库（CBM）、维普中文科技期刊数据库（VIP）、中国知识资源总库（CNKI）中有关中医治疗早期糖尿病肾病的随机对照试验。依据修改后Jadad量表对纳入文献评分并采用Rev. Man 5.3软件进行Meta分析。


结果 共纳入27个随机对照试验，涉及1824名早期糖尿病肾病患者。Meta分析显示，与单纯使用血管紧张素转化酶抑制剂及血管紧张素II受体拮抗剂（ACEI/ARB）的对照组相比，无论治疗组是否使用ACEI/ARB均可以有效降低尿微量白蛋白排泄率（UAER）水平和尿微量白蛋白/肌酐比，减少24h尿蛋白定量，且无严重不良反应。 结论 中药治疗早期糖尿病肾病是安全和有效的。

• Objective To evaluate the effects of Traditional Chinese Medicine(TCM) on

proteinuria in patients with early diabetic nephropathy (DN) by using meta-analysis. • Methods All publications of randomized controlled trials (RCTs) studying traditional

Chinese medicine in the treatment of early diabetic nephropathy were searched and

identified from Medline、PubMed、Cochrane library, CBM, VIP and CNKI. The quality of included studies were evaluated by using revised Jadad scale. Rev. Man 5.3 was adopted for meta-analysis.

Results A total of 27 RCTs involving 1824 patients with early DN were included. Meta-analysis results showed that TCM treatment group could reduce the level of urine albumin excretion rate (UAER) and 24h urine albumin level with or without using angiotensin converting enzyme inhibitor and angiotensin receptor blocker (ACEI/ARB), when compared to control group using ACEI/ARB only. No serious adverse reactions were observed in TCM treatment groups.

Conclusion It was proved that Chinese medicine is safe and effective in treating patients with early diabetic nephropathy.

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目的 探讨对肺炎患儿进行综合护理的效果。

方法 将2015年6月至2017年6月三台县人民医院收治的96例肺炎患儿采用随机数表法分为观察组（n=48）和对照组（n=48）。对对照组患儿进行常规治疗及护理，在此基础上对观察组患儿进行综合护理，然后对比观察两组患儿在接受治疗及护理后观察组患儿退热的时间、肺部啰音消失的时间、咳嗽消失的时间和住院的时间，并评估其临床疗效。

结果 与对照组患儿相比，在接受治疗及护理后观察组患儿退热的时间、肺部啰音消失的时间、咳嗽消失的时间和住院的时间均较短，差异有统计学意义。观察组患儿治疗的总有效率为95.83%，对照组患儿治疗的总有效率为81.25%，二者相比差异有统计学意义（P‹0.05）。

结论 对肺炎患儿进行综合护理能取得理想的临床效果，可较快改善其临床症状及体征，并可缩短其住院时间。

Objective To explore the effect of comprehensive nursing for children with pneumonia. Methods 96 children with pneumonia admitted to the People’s Hospital of Santai County from June 2015 to June 2017 were included and divided into observation group （n=48）and control group（n=48）.On the basis of routine treatment and nursing for children in the control group, comprehensive nursing was performed/conducted in the observation group. Then the time of fever abatement，lung rale disappearance, cough disappearance and hospitalization were compared between the two groups after receiving treatment and nursing, and the clinical efficacy was evaluated.

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Rusults Compared with the control group, the time of fever abatement, lung rale disappearance, cough disappearance and hospitalization in the observation group were all shorter after treatment and nursing, and the difference was statistically significant.The total effective rate of treatment was 95.83% in the observation group and 81.25% in the control group. There was significant difference between the two groups (P<0.05). Conclusion Comprehensive nursing for children with pneumonia can achieve ideal clinical effect, improve their clinical symptoms and signs quickly, and shorten their hospitalization time.

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